AMPKa2

AMPKa2 (AMP-A2B1G1) assay

Protein kinase AMP-activated catalytic subunit alpha 2

Synonyms: PRKAA2

Family: CAMK (Calcium and Calmodulin-regulated kinases)

AMPK, AMP-activated protein kinase, is a key regulator of intracellular fatty acid metabolism and a positive regulator of insulin sensitivity1. AMPKa is the catalytic subunit of AMPK, which has two isoforms AMPKa1 and AMPKa2.

AMPKa2 assay is run on mobility shift microfluidics platform, which provides best in industry quality of data (Caliper). We routinely run services associated with this kinase including: screening, profiling, dose-response studies and kinetic measurements. Please contact us for more information.

References:

1. Liu Y, Wan Q, Guan Q, Gao L, Zhao J. High-fat diet feeding impairs both the expression and activity of AMPKa in rats’ skeletal muscle. Biochemical and biophysical research communications. 2006 Jan 13;339(2):701-7.