DGK alpha assay
Diacylglycerol kinase alpha
Synonyms: DGK-alpha, DAGK, DAGK1, DGKA
DGKA is one of ten DGK enzymes that convert the membrane lipid diacylglycerol into phosphatidic acid1. Both diacylglycerol and phosphatidic acid play important roles in cellular signaling, they act as important second messengers and can bind directly to and modulate numerous proteins in cancer.
DGK alpha kinase assay is run on mobility shift microfluidics platform (Caliper), which provides best in industry quality of data. We routinely run services associated with this kinase including: screening, profiling, dose-response studies and kinetic measurements. Please contact us for more information.
1. Purow B. Molecular pathways: targeting diacylglycerol kinase alpha in cancer. Clinical Cancer Research. 2015 Nov 15;21(22):5008-12.