G protein-coupled receptor kinase 3
Synonyms: BARK2, ADRBK2
GRK3 is a receptor kinase that specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. GRK3 is ubiquitously expressed throughout the body. It regulates the desensitization of odorant receptors and α2-adrenergic receptors playing role in olfaction and neuronal functions1.
GRK3 kinase assay is run on mobility shift microfluidics platform (Caliper), which provides best in industry quality of data. We routinely run services associated with this kinase including: screening, profiling, dose-response studies and kinetic measurements. Please contact us for more information.
1. Steury MD, McCabe LR, Parameswaran N. G protein-coupled receptor kinases in the inflammatory response and signaling. InAdvances in immunology 2017 Jan 1 (Vol. 136, pp. 227-277). Academic Press.