G protein-coupled receptor kinase 5
GRK5 is a receptor kinase and a member of G protein-coupled receptor kinase family, which has been shown to play a critical role in the outcome of a variety of physiological and pathophysiological processes including chemotaxis, signaling, migration, inflammatory gene expression, etc1. GRK5 was shown to play important role in cholinergic responses and inflammation.
GRK5 kinase assay is run on mobility shift microfluidics platform (Caliper), which provides best in industry quality of data. We routinely run services associated with this kinase including: screening, profiling, dose-response studies and kinetic measurements. Please contact us for more information.
1. Steury MD, McCabe LR, Parameswaran N. G protein-coupled receptor kinases in the inflammatory response and signaling. InAdvances in immunology 2017 Jan 1 (Vol. 136, pp. 227-277). Academic Press.