Inhibitor of nuclear factor kappa B kinase subunit epsilon
Synonyms: IKK-i, IKKE, KIAA0151, IKBKE
IKK-EPSILON is IKK-related kinase, which plays role in immune signaling, has impact on cell proliferation and transformation, and is thereby classified as an oncogene1. It is preferentially expressed in T cells and peripheral blood cells2.
IKK-EPSILON kinase assay is run on mobility shift microfluidics platform (Caliper), which provides best in industry quality of data. We routinely run services associated with this kinase including: screening, profiling, dose-response studies and kinetic measurements. Please contact us for more information.
1. Verhelst K, Verstrepen L, Carpentier I, Beyaert R. IκB kinase ɛ (IKKɛ): A therapeutic target in inflammation and cancer. Biochemical pharmacology. 2013 Apr 1;85(7):873-80.
2. Häcker H, Karin M. Regulation and function of IKK and IKK-related kinases. Sci. Stke. 2006 Oct 17;2006(357):re13-.