INSR

INSR is tyrosine kinase and transmembrane receptor, which is activated by insulin, IGF-I and IGF-II. INSR initiates a cascade of cellular phosphorylation reactions that regulate protein interactions and enzymatic activities. Substrates of the INSR include the insulin receptor substrates IRS-1 and IRS-2, as well as Shc and APS¹.

INSR kinase assay is run on mobility shift microfluidics platform (Caliper), which provides best in industry quality of data. We routinely run services associated with this kinase including: screening, profiling, dose-response studies and kinetic measurements. Please contact us for more information.