Dual specificity tyrosine phosphorylation regulated kinase 4
DYRK4 is a dual specificity tyrosine kinase, which could phosphorylate both Ser/Thr and Tyr substrates. DYRK4 is the least studied DYRK family member1.
DYRK4 kinase assay is run on mobility shift microfluidics platform (Caliper), which provides best in industry quality of data. We routinely run services associated with this kinase including: screening, profiling, dose-response studies and kinetic measurements. Please contact us for more information.
1. Papadopoulos C, Arato K, Lilienthal E, Zerweck J, Schutkowski M, Chatain N, Müller-Newen G, Becker W, de la Luna S. Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity. Journal of Biological Chemistry. 2011 Feb 18;286(7):5494-505.