KIT proto-oncogene receptor tyrosine kinase
Synonyms: C-Kit, CD117, SCFR, PBT
KIT is a receptor tyrosine kinase, which is essential for normal hematopoiesis1. Kit is mainly considered a stem cell factor, which participates in vital functions of the human body, such as fertility, homeostasis, and melanogenesis2.
KIT kinase assay is run on mobility shift microfluidics platform (Caliper), which provides best in industry quality of data. We routinely run services associated with this kinase including: screening, profiling, dose-response studies and kinetic measurements. Please contact us for more information.
1. Galanis A, Levis M. Inhibition of c-Kit by tyrosine kinase inhibitors. Haematologica. 2015 Mar 1;100(3):e77-9.
2. Babaei MA, Kamalidehghan B, Saleem M, Huri HZ, Ahmadipour F. Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells. Drug design, development and therapy. 2016;10:2443.