EPH-A8 assay
EPH receptor A8
Synonyms: Hek3, EEK
Family: TK
EPHA8 is a receptor tyrosine kinase that is involved in angiogenesis, cell adhesion and migration1. Binding and activation of Eph-receptor family members requires cell-cell interactions2.
EPHA8 kinase assay is run on mobility shift microfluidics platform (Caliper), which provides best in industry quality of data. We routinely run services associated with this kinase including: screening, profiling, dose-response studies and kinetic measurements. Please contact us for more information.
References:
1. Liu X, Xu Y, Jin Q, Wang W, Zhang S, Wang X, Zhang Y, Xu X, Huang J. EphA8 is a prognostic marker for epithelial ovarian cancer. Oncotarget. 2016 Apr 12;7(15):20801.
2. Kullander K, Klein R. Mechanisms and functions of Eph and ephrin signalling. Nature reviews Molecular cell biology. 2002 Jul;3(7):475.