FYN proto-oncogene, Src family tyrosine kinase
Synonyms: MGC45350, SLK, SYN
FYN is a member of the Src tyrosine kinase family, and it is known to be involved in several biological activities such as cell growth associated with cancer. Fyn expression is upregulated in multiple human cancers including prostate cancer, glioblastoma, chronic myelogenous leukemia, melanoma and squamous cell carcinoma, and associated with tumor metastasis1.
FYN kinase assay is run on mobility shift microfluidics platform (Caliper), which provides best in industry quality of data. We routinely run services associated with this kinase including: screening, profiling, dose-response studies and kinetic measurements. Please contact us for more information.
1. Lyu SC, Han DD, Li XL, Ma J, Wu Q, Dong HM, Bai C, He Q. Fyn knockdown inhibits migration and invasion in cholangiocarcinoma through the activated AMPK/mTOR signaling pathway. Oncology Letters. 2018 Feb 1;15(2):2085-90.