Insulin receptor related receptor
IRR is a member of a family of receptors that includes the insulin receptor (IR) and the insulin-like growth factor I receptor1. IRR is expressed in the human kidney, heart, skeletal muscle, liver, and pancreas, and the tyrosine kinase of IRR appears to be similar to that of IR in both the spectrum of substrates phosphorylated and the biological responses stimulated.
IRR kinase assay is run on mobility shift microfluidics platform (Caliper), which provides best in industry quality of data. We routinely run services associated with this kinase including: screening, profiling, dose-response studies and kinetic measurements. Please contact us for more information.
1. Zhang B, Roth RA. The insulin receptor-related receptor. Tissue expression, ligand binding specificity, and signaling capabilities. Journal of Biological Chemistry. 1992 Sep 15;267(26):18320-8.